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- _5 value "Go6976 inhibits the classical PKC isoforms and PKCmu, whereas Go6983 suppresses kinase activity of PKC isoenzymes from all 3 major subgroups but does not effectively inhibit PKCmu...Pretreatment of H929 cells with Go6976 or Go6983 for 1 hour inhibited migration through the HS-27 cell line in a dose-dependent manner...Taken together, these observations with results from the translocation studies suggest that Wnt-mediated migration is PKCdependent and that PKCmu is one member of this family facilitating the migratory process." provenance.
- _5 wasQuotedFrom 15886323 provenance.