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- _6 value "TAK1 is subsequently activated in the cytoplasm, leading to the activation of IKK. Inactive IKK sequesters NF-?B in the cytoplasm, but activation leads to phosphorylation and degradation of I?B and consequent release of NF-?B. Activation of TAK1 also results in the activation of MAP kinases and c-Jun NH2-terminal kinase (JNK)." provenance.
- _6 wasQuotedFrom 12893815 provenance.