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- _3 value "IKK-i is expressed mainly in immune cells, and is induced in response to proinflammatory cytokines such as tumor necrosis factor-alpha, IL-1 and IL-6, in addition to LPS. We examined whether other stimuli induce IKK-i expression. Stimulation of RAW264.7 cells with IL-6 and IFN-{gamma} induced IKK-i mRNA expression. IKK-i mRNA expression was up-regulated upon stimulation of thioglycollate-elicited peritoneal macrophages with TNF-{alpha}, IL-1�, IFN-{gamma} and IL-6 in addition to LPS. In contrast, mRNA expression levels of IKK-{alpha} or IKK-� were not augmented in response to these stimuli." provenance.
- _3 wasQuotedFrom 10421793 provenance.