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- _6 value "Treatment of IKK2 mutant macrophages with lippolysaccharides (LPS, an activator of IKBKB activity) showed approximately 40-50% less p65 activation at 10 and 60 minutes, respectively when compared with control. In addition, immunocytochemistry revealed that approximately 20% of IKK2 deleted cells did not show nuclear translocation of p65 after LPS stimulation, whereas control showed >95% translocation. This indicates that LPS induced activation of p65 was mediated by IKK2." provenance.
- _6 wasQuotedFrom 14561702 provenance.