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- _4 value "we tested the ability of two PI3-K inhibitors, LY294002 and wortmannin, to inhibit Akt/PKB phosphorylation. Fig. 2A shows that both LY294002 and wortmannin completely inhibited phosphorylation of S473 in the three NSCLC cell lines that maintain S473 phosphorylation under serum deprivation. Native Akt/PKB levels did not change. Similar results were obtained for T308 phosphorylation (Fig. 2B)." provenance.
- _4 wasQuotedFrom 11358816 provenance.