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{ <http://www.tkuhn.ch/bel2nanopub/RAdsmcIKAFXMSVyZy4zHepwKKxqnX7Eyrg-QdQFfnJdfA#_4> ?p ?o ?g. }
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(Harrington et al., 2004). The mechanism of this transcriptional repression depends on the activation of mTORC1 signaling, as rapamycin treatment and silencing of S6K genes restores IRS-1 levels.
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