Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAdwFXYzN31mbyNdIiL1x_u3xea2IcBzQh5KxopKEZVMI#_6> ?p ?o ?g. }
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- _6 value "In human thyroid tissue, the ligand-independent activation of the adenylyl cyclase may be caused by mutations affecting two elements of the cAMP pathway, the TSH receptor, or the Gs protein itself ...gain of function mutations of TSH receptors or Gs. Moreover, we provide biochemical and molecular evidence for the induction of specific PDE isoforms in the presence of constitutive activation of the cAMP cascade induced by these oncogenes. ...the ATAs bearing constitutively active mutant TSH receptors" provenance.
- _6 wasQuotedFrom 10946896 provenance.