Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAeVwlmhMg-0hDS32VqFz7vPc6JMU4O7Bu9j3H3dk1CyE#_4> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _4 value "Once phosphorylated, Cbl can recruit the SH2-containing adaptor protein CrkII to lipid rafts, along with the GEF C3G. C3G then appears to activate the Rho family GTPase TC10. This small GTP-binding protein is produced in fat and muscle and can be acutely activated by insulin in a CAP-dependent but PdtIns-3-kinase-independent manner. Activation of TC10 is specific for insulin, and disruption of its activation blocks insulin-stimulated glucose transport and Glut4 translocation." provenance.
- _4 wasQuotedFrom 11849969 provenance.