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- _3 value "We determined the lowest effective concentrations for three commonly prescribed statins (atorvastatin, simvastatin, rosuvastatin) and a newly-available statin (pitavastatin) (Fig. 5A?D). All four statins produced a clear reduction in ABCA1 and ABCG1 mRNA expression in THP-1 macrophages at concentrations of 50?100 nM. These effects were also seen in HMDMs at 100nM and higher (Fig. 5E)," provenance.
- _3 wasQuotedFrom 17466310 provenance.