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- _3 value "Gene expression changes in other functional groups. Hypoxia also resulted in an increase in the expression of vascular endothelial growth factor C (VEGFC), although this was not statistically significant. Additionally, we observed a significant increase in the expression of plasminogen activator inhibitor type 1 (SERPINE1). This increase was confirmed by real-time RT-PCR (Fig. 1). We also found that a number of genes encoding proteins involved in mediating a cytoprotective response to oxidant stress were reduced by hypoxia, including metallothionein 2A (MT2A), biliverdin reductase A (BLVRA), and GABAB-related G-protein coupled receptor (GABABL)." provenance.
- _3 wasQuotedFrom 15100389 provenance.