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- _7 value "This finding lead Chen et al. to propose a model for the action of rapamycin whereby rapamycin/FKBP12 binds to mTOR, preventing interaction with PA (3, 6). Consistent with the proposal that the rapamycin/FKBP12 complex acts competitively with PA, elevated PLD activity in human breast cancer cells increased the concentration of rapamycin required to suppress mTOR" provenance.
- _7 wasQuotedFrom 17210675 provenance.