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- _6 value "PDE3s are activated when phosphorylated either by cAMP-dependent protein kinase (PKA) or by phosphatidyl inositol-3-phosphate-dependent protein kinase (Manganiello and Degerman, 1999). In addition, cAMP-elevating agents increase PDE3 activities and levels in several cell types (Degerman et al., 1997), including cultured rat and human aortic vascular smooth muscle cells (Rose et al., 1997; Liu and Maurice, 1998; Palmer and Maurice, 2000)." provenance.
- _6 wasQuotedFrom 14692693 provenance.