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- _5 value "To confirm that TNFalpha protein synthesized in the brain of the transgenic animal is biologically active, we quantified expression of TRADD protein. Homogenates of brain sampled from TNFalpha-Tg and non-Tg rats were incubated with a primary antibody that recognizes rat TRADD only after it has been activated through binding of TNFalpha to p55/TNFR1, thereby implying biological activity of the cytokine. Regional expression of TRADD protein was uniformly higher in TNFalpha-Tg rat brain than in non-Tg controls by statistically significant margins." provenance.
- _5 wasQuotedFrom 18947406 provenance.