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- _4 value "IL-6 and KC, the latter of which is a murine CXC homologue of human GRO, are two endogenously expressed LPS- and IL-1b-inducible gene products, the expression of which is dependent upon NF-kB activation (25, 26). Similar to luciferase activity, IL-6 production (Figure 2c) and KC production (Figure 2d) were both enhanced in FADD-/- MEFs compared with FADD+/+ MEFs following LPS or IL-1b exposure. Together, these data demonstrate that NF-kB-dependent gene expression is enhanced in the absence of FADD. " provenance.
- _4 wasQuotedFrom 11828002 provenance.