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- _5 value "Several proteins have been implicated in regulating the formation of the ternary complex - which consists of Syntaxin 4, SNAP23, and VAMP2 - in response to insulin. For example, Synip binds to Syntaxin 4 and prevents VAMP2, but not SNAP23, binding. The association of Synip with Syntaxin 4 is reduced on stimulation with insulin... Similarly, the VAMP2-binding proteins pantophysin and vesicle-associated protein 33 (VAP33) have been proposed to prevent the entry of the v-SNARE into the ternary complex in the absence of insulin." provenance.
- _5 wasQuotedFrom 11994746 provenance.