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- _5 value "Microarray studies performed with an NIH 3T3 cell line engineered to express an inducible Arf gene identified numerous p19Arf-responsive genes that were temporally regulated in either a p53-dependent or -independent manner (33). Among these, the Hzf gene (gene identifier 7305176) encoding a previously described \"hematopoietic zinc finger\" (Hzf) protein (23) was rapidly induced with kinetics similar to that of the bona fide p53-regulated target gene, Mdm2. The failure of exogenously expressed p19Arf to increase Hzf mRNA levels in p53-null MEFs indicated that Hzf expression is p53 dependent." provenance.
- _5 wasQuotedFrom 16382142 provenance.