Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAiQCPR7UO_IkxzyZ4fUXbcIcJKnYiWJPHyxDPKmVR-hg#_4> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _4 value "The presence of a consensus binding site (CGCCCCCGC) for the transcription factor Egr-1 (synonymous with Krox-24, NGFI-A, Zif268, and TIS-8) at bp -163 is particularly notable. This site has been shown to bind a family of zinc finger proteins that are immediate early response genes important in growth regulation. Egr-1 expression is rapidly and transiently induced by nerve growth factor in PC12 cells and by serum in fibroblasts. Of particular relevance is the observation that Egr-1 is induced during the G/G transition in the cell cycle after mitogenic stimulation of T lymphocytes, as well as during G as a separate event mediated by interleukin-2." provenance.
- _4 wasQuotedFrom 7896827 provenance.