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- _4 value "This disruption in ureagenesis may be explained by a marked decrease in expression and activity of hepatic ornithine transcarbamylase (OTC). ...it was established that high levels of promoter activity were dependent on both HNF4alpha-binding sites and the expression of HNF4alpha Mice lacking hepatic HNF4alpha expression exhibited increased serum ammonia and reduced serum urea." provenance.
- _4 wasQuotedFrom 11994307 provenance.