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- _5 value "In lung fibroblasts, elastase is known to initiate shedding of heparan sulfate proteoglycans (17), extracellular molecules serving as docking sites for multiple growth factors, such as basic fibroblast growth factor (bFGF) and transforming growth factor (18, 19). This shedding, in turn, leads to reduction of bFGF binding to its high affinity receptors (17)." provenance.
- _5 wasQuotedFrom 11889128 provenance.