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- _4 value "The proto-oncogene c-myc can promote cell death (probably mediated through p53) or cell proliferation, depending on its expression level. It functions as a nuclear phosphoprotein with particular properties of a transcription factor [68,69]. In serum deprived cultures, cells overexpressing c-myc readily undergo apoptosis. In addition, deregulation of c-myc causes apoptosis of VSMCs deprived of growth factors or treated with cytokines such as interferon-g [70]." provenance.
- _4 wasQuotedFrom 12928037 provenance.