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- _6 value "CD40 lacks intrinsic catalytic activity, but the cytoplasmic domain of CD40 has two binding sites for TRAF...TRAFs 1, 2, 3, 5, and 6 have been found in association with CD40, and these adaptors couple CD40 to the phosphoinositide 3-kinase (PI3K), phospholipase C�?³ (PLC-�?³), mitogen-activated protein kinase (MAPK-ERK, p38, and JNK), and nuclear factor �?ºB (NF-�?ºB) signaling pathways" provenance.
- _6 wasQuotedFrom 15199223 provenance.