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- _5 value "Fig. 4. Regulation of gene expression by BSAP in pre-BI cells. (A) 10-fold reduction of mb-1, LEF-1, N-myc and bcl-xL transcription and derepression of the PD-1 and c-myc genes in Pax-5-deficient pre-BI cells.............Hence, the BSAP? ER protein can be activated by estrogen addition even in the presence of the translational inhibitor cycloheximide (CHX) blocking all protein synthesis. Under these conditions, BSAP?ER is still able to induce transcription of CD19, mb-1, N-myc and LEF-1, thus demonstrating that all four genes are directly controlled by BSAP (Figure 6A)." provenance.
- _5 wasQuotedFrom 9545244 provenance.