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- _4 value "A-fos significantly interrupted TGF-beta 1-induced suppression of Dlx5 (Fig. 6C, lanes 3 and 5). Among several AP-1 components, c-Jun protein showed a differential expression pattern between TGF-beta 1 and BMP-2; c-Jun protein level was significantly increased by TGF-1 but not by BMP-2 (Fig. 6D). Consistent with these results, the overexpression of c-Jun alone mimicked the antagonistic action of TGF-1 in BMP-stimulated Dlx5 expression (Fig. 6C, lanes 2, 3, 6, and 7)." provenance.
- _4 wasQuotedFrom 12815054 provenance.