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- _5 value "S1P, in physiologic concentrations, preferentially activates the small GTPase Rac via S1P1 in a pertussis toxin-sensitive fashion and enhances barrier integrity, whereas thrombin preferentially stimulates Rho and causes cell contraction and barrier disruption (van Nieuw Amerongen et al., 2004; Vouret-Craviari et al., 2002)." provenance.
- _5 wasQuotedFrom 18973762 provenance.