Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAnOyoj_QakUptdj4cSzGOf1ub5L4-bQIpTKvreC1TO1k#_5> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _5 value "Figure 5. This is a figure in the review representing the cross talk between FGFR3 and IL6 signaling in multiple myeloma cell line KH11; the legend is as follows: Fig. 5. Enhanced proliferation of myeloma cells by interleu- kin- 6 cooperatingwith FGFR3-mediated signals. IL- 6 and FGF induce the distinct intracellular signaling pathways in myeloma cells carryingt(4 ;14)(p16. 3 ;q32) that ectopically express FGFR3. FGF and IL- 6 activate ERK1/ 2, PI- 3 kinase and STAT3, respectively. The serine phosphorylation of STAT3 via the FGF- induced ERK1/ 2 activation contributes to the full activation of STAT3, leadingto the expression of c-myc and bcl- 2 genes and cell proliferation 91 .FRS:FGF receptor substrate." provenance.
- _5 wasQuotedFrom 17142955 provenance.