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- _4 value "wild-type FLAG-OREBP-(1-581)-?1-131 resided in the nucleus under isotonic conditions and was localized to the cytoplasm in response to hypotonic challenge (Fig. 1B). All the alanine mutants remained responsive to hypotonic challenge except for the alanine substitution at Ser-155 (S155A) (Fig. 1B), indicating that this amino acid plays an important role in nuclear exclusion of OREBP/TonEBP. " provenance.
- _4 wasQuotedFrom 18411282 provenance.