Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAnsWvfTpJ_j0TO-uUdFZTbaZtVqlZcpl6B_c2kCzBaUI#_5> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _5 value "In addition to reduced expression of the genes encoding insulin, glucose transporter-2, L-pyruvate kinase, aldolase B and 3-hydroxy-3-methylglutaryl coenzyme A reductase, induction of HNF1 alpha-P291fsinsC also significantly inhibits expression of mitochondrial 2-oxoglutarate dehydrogenase (OGDH) E1 subunit mRNA and protein. OGDH enzyme activity and [(14)C]pyruvate oxidation were also reduced. In contrast, the mRNA and protein levels of mitochondrial uncoupling protein-2 were dramatically increased by HNF1 alpha-P291fsinsC induction." provenance.
- _5 wasQuotedFrom 10944108 provenance.