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- _3 value "In addition, increased HO-1 expression levels have clinically been demonstrated in a wide variety of inflammatory conditions, such as ischemia/reperfusion injury, atherosclerosis, asthma, Alzheimer disease, and acute renal failure (Amersi et al., 1999; Siow et al., 1999; Agarwal and Nick, 2000; Maines, 2000; Tullius et al., 2001). Moreover, HO-1 production is greatly elevated in inflammatory cells during the resolution phase of inflammation (Fig. 6) (Willis et al., 1996)." provenance.
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