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- _3 value "Since PPARs have been shown to activate LPL gene expression at the transcriptional level via a PPRE in its promoter [21], the influence of PPAR agonists on LPL gene expression in human macrophages was evaluated The average relative increase of LPL mRNA normalized to control 36B4 mRNA levels, as determined by two independent experiments on different macrophage preparations, was approximately 3-, 4-, 3-, and 3.4-fold for rosiglitazone (50 nM), Wy14643 (20 M), GW2331 (200 nM) and PG-J2 (1 M), respectively" provenance.
- _3 wasQuotedFrom 11852057 provenance.