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- _4 value "and protein phosphatases (Immenschuh et al., 2000). However, HO-1 gene expression is often cell type- and species-specific (Morse and Choi, 2002). Consistent with the diversity of signaling cascades involved in HO-1 induction, the promoter region of HO-1 contains a wide variety of regulatory elements (Abraham et al., 1996). It includes DNA-binding sites for oxidative stress-responsive transcription factors, such as nuclear factor (NF)-B, NF-E2-related factor 2 (Nrf2), and AP-1 (Lavrovsky et al., 1994; Choi and Alam, 1996). " provenance.
- _4 wasQuotedFrom 12869663 provenance.