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- _9 value "STRAD interaction and cytosolic localization appear to be required for the capacity of LKB1 to induce G1 growth arrest in an LKB1-deficient cancer cell line (G361 melanoma cells) as an LKB1 point mutation identified in a PJS kindred that abrogates this interaction, but does not compromise kinase activity, fails to promote G1 arrest (Baas et al., 2003)." provenance.
- _9 wasQuotedFrom 19029933 provenance.