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- _8 value "We used a luciferase reporter construct that contains CAGA elements which are sites of direct DNA binding for activated Smad3 (CAGA(12)-luc).35 We observed that Epac1 strongly inhibited TGFbeta/TbetaRI-dependent activation of CAGA(12)-luc in Mv1Lu cells, as compared to cells transfected with TbetaRI alone (Figure 7A, B)." provenance.
- _8 wasQuotedFrom 17203972 provenance.