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- _4 value "ex vivo studies of macro-phages derived from Smad3?/? mice demonstrated a more activated phenotype with enhanced induction of MCP-1 secretion in response to LPS. Importantly, while TGF-?1 inhibited LPS-stimulated MCP-1 production from Smad3+/+ mice, this TGF-?1 inhibition was completely blocked in macrophages from Smad3?/? mice.79" provenance.
- _4 wasQuotedFrom 16462725 provenance.