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- _7 value "Triggering of the IL-1R or TLR causes the adaptor protein MyD88 to be recruited to the receptor complex, which in turn promotes association with the IL-1R-associated kinases IRAK4 and IRAK1. During the formation of this complex, IRAK4 is activated, leading to the hyperphosphorylation of IRAK-1, which then induces the interaction of TRAF6 with the complex." provenance.
- _7 wasQuotedFrom 12893815 provenance.