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- _5 value "IL-1beta markedly induced the luciferase activity in the MH7A cells transfected with the luciferase reporter plasmid carrying the IL-6 promoter. The luciferase activity was significantly decreased when the region (-159 to -142bp) was deleted which includes the C/EBPbeta consensus element. A 5bp mutation introduced into the C/EBPbeta binding element reduced the induction of IL-6 promoter in response to IL-1beta to 40%." provenance.
- _5 wasQuotedFrom 9516466 provenance.