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- _5 value "Phosphorylation at Thr183 resulted in increases in the rate of phosphotransfer and the overall turnover rate, both of ?80-fold, and a partial (2.5-fold) restoration of the lowK m (MBP) displayed by [PP]ERK2. The increased catalytic commitment of MBP in response to phosphorylation at Thr183 is attributable mostly to the 80-fold increase in the rate of phosphoryl group transfer, as opposed to only minor changes in MBP binding affinity. " provenance.
- _5 wasQuotedFrom 11524422 provenance.