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- _4 value "in the presence of insulin, stimulation with CCK-8 led to a dramatic accumulation of cyclin D1, comparable to that induced by EGF and insulin. Addition of CCK-8 in the presence of EGF also induced a marked increase in the level of cyclin D1. As shown in Figure 8, addition of CCK- 8 to Swiss 3T3 CCKBRGFP cells also promoted a striking increase in the level of cyclin D3 in the presence of insulin or EGF. Accordingly, addition of CCK-8 in combination with either insulin or EGF also induce a striking accumulation of cyclin E." provenance.
- _4 wasQuotedFrom 11748587 provenance.