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- _6 value "ROCK1 and -2, alternatively, activate LIM domain-containing protein kinase 1 (LIMK1) and 2 (LIMK2), which phosphorylate and inhibit the actin depolymerization factor cofilin (cofilin-P). This increases actin polymerization and results in the stabilization of actin stress fibres27. The phosphatase slingshot dephosphorylates cofilin, which blocks actin polymerization." provenance.
- _6 wasQuotedFrom 15573116 provenance.