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- _4 value "Overexpression of VEGFC in skin keratinocytes leads to dermal lymphatic-vessel hyperplasia 16. Signalling by means of VEGFR3 alone was shown to be sufficient for the hyperplasia, as transgenic mice that overexpress a mutant form of VEGFC, which has lost its capacity to bind VEGFR2 and only binds and activates VEGFR3 (VEGFC156S), was able to induce a similar phenotype 20." provenance.
- _4 wasQuotedFrom 12154350 provenance.