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- _5 value "To identify the modified residue, the relevant tryptic peptides from each sample were further analyzed by tandem mass spectrometry. Comparison of the fragment patterns revealed that Asn 851 contained the additional oxygen atom (Fig. 4B). Together these data show that FIH-1 is an asparaginyl hydroxylase that inhibits HIF transcriptional activity by preventing CAD association with the coactivator p300. " provenance.
- _5 wasQuotedFrom 12080085 provenance.