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- _4 value "As shown in Figure 1, LPS resulted in a strong induction of both TNF-? and IL-6. In the case of TNF-?, maximum concentrations were reached by 2 hours and were markedly higher in the SR-BI?null mice than in control mice (Figure 1A). In the case of IL-6, LPS-induced plasma concentrations reached nearly similar maximal levels in both SR-BI?null and control mice after 2 hours (Figure 1B). However, IL-6 levels in control mice returned to baseline levels after 8 hours, whereas the level of IL-6 in SR-BI?null mice remained elevated for 24 hours before dropping to baseline levels by 48 hours." provenance.
- _4 wasQuotedFrom 18064300 provenance.