Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RArjXrPM-8QI27SR_0C4-LEuYqOqhFBeiXgQfPN_I4keo#_6> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _6 value "IL-6-induced Association of Gab1 and Gab2 with SHP2 Is Hck-mediated.....IL-6-induced tyrosine phosphorylation of Gab1 and Gab2, as well as their association with SHP2, were markedly decreased in MM cells with kinase-inactive Hck versus MM cells with wild-type Hck. In anti-Grb2 immunoprecipitates, IL-6-induced tyrosine phosphorylation of Gab1 and Gab2, but not their association with Grb2, was abrogated (Fig. 6b). Taken together, these data further confirm that IL-6-induced Gab protein tyrosine phosphorylation and formation of Gab/Grb2�SHP2-containing protein complexes is dependent on Hck activity." provenance.
- _6 wasQuotedFrom 15010462 provenance.