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- _5 value "However, it has recently been shown that MTF-1, functioning as a metalloregulatory transcription factor, activates metallothionein genes in response to the essential metal zinc. Dissection of the zinc-finger domain revealed that finger 1 of MTF-1 constitutes a unique metal-sensing domain that, in cooperation with the transactivation domains, produces a zinc-sensing metalloregulatory transcription factor (Bittel et al., 2000)." provenance.
- _5 wasQuotedFrom 11230134 provenance.