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- _3 value "HFL-1 cells were pretreated with SC-514, a selective inhibitor of NF-B-dependent gene expression (32), followed by treatment with either 2% CSE or IL-1. SC-514 was able to attenuate IL-1-induced Cox-2 induction (Fig. 8B), suggesting that it was effective in blocking NF-B-dependent gene expression. Western blot analysis revealed that SC-514 was also partially effective in blocking the induction of HO-1 by 2% CSE (Fig. 8B). Densitometric analysis revealed that SC-514 inhibited HO-1 by 45% (Fig. 8B)." provenance.
- _3 wasQuotedFrom 18689604 provenance.