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- _4 value "Phosphorylation of a tyrosine residue at 705 in STAT3 is observed in KMS-11 in response to IL-6. In contrast, bFGF induces the activation of ERK1/2 and PI-3 kinase. These results indicate that IL-6 and bFGF activate the distinct intra- cellular signaling pathways, and both the ERK1/2 and PI-3 kinase pathways activated by bFGF are necessary for the enhanced proliferation of KMS-11. " provenance.
- _4 wasQuotedFrom 17142955 provenance.