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- _6 value "CaMKKc and Akt overexpression decreases IRAK1-mediated NF-?B activity and its association with MyD88 in response to IL-1? stimulation. Furthermore, CaMKKc and Akt overexpression increases IRAK1 phosphorylation at Thr100, and point mutation of this site abrogates the inhibitory effect of Akt on IRAK1-mediated NF-?B activation." provenance.
- _6 wasQuotedFrom 11976320 provenance.