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- _3 value "Nuclear translocation of NF-kappaB was demonstrated after 30 minutes of treatment of Rheumatoid synovial fibroblasts with TNF-alpha at concentrations > 10pg/ml. However, when 100 ng/ml TRX was added 1hour before TNF addition, The NF-kappaB nuclear translocation was significantly promoted. At a TNF-alpha concentration between 10 and 100 pg/ml, significant effects of the addition of TRX in promoting the nuclear translocation of NF-kappaB were observed.p<0.05; p<0.01. The percent nuclear translocation of NF-kappaB was augmented by addition of TRX in the presence of 10pg/ml TNF-alpha(48.7 +/- 7.9% vs 23.3 +/- 6.3%, p<0.01)." provenance.
- _3 wasQuotedFrom 10384135 provenance.