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- _5 value "Apoptosis is executed through the activation of caspases. To further verify the effect of tobacco smoke in the induction of apoptosis, the levels of cleaved caspases 8, 9, and 3 in rat lungs were determined. In agreement with the apoptotic results described above, exposure of rats to 80 mg/m3 tobacco smoke resulted in significantly increased levels of cleaved caspases 8, 9, and 3, indicating the activation of these caspases (Fig. 7B). Compared to FA control animals, the cleaved caspases 8, 9, and 3 were elevated by 98.1%, 113.9%, and 84.7 %, respectively." provenance.
- _5 wasQuotedFrom 18355884 provenance.