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- _3 value "Next, we asked whether Zeb1 acts directly on the p21Cdkn1a and p15Ink4b gene promoters. In ChIP assays, Zeb1 was bound to both promoters, but no interaction was seen with the control Gapdh promoter (Fig. 8C-E). These results are consistent with the notion that Zeb1 is represses these CDKIs directly by binding to their promoters in vivo." provenance.
- _3 wasQuotedFrom 18192284 provenance.