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- _5 value "Transgenic mice with a 100% increase in the expression of GPX-1 have an increased carcinogenic response to initiation by 7,12-dimethylbenz[a]anthracene followed by promotion with a phorbol acetate. 7,12-dimethylbenz[a]anthracene^Carcinogenesis induced carcinogenesis = % phorbol_carc = Tetradecanoylphorbol acetate^induced carcinogenesis Gpx1^phorbol_carc Over-expression of human Gpx1 can also protect mice against the neurotoxin 6-hydroxydopamine. Gpx1-|6-hydroxydopamine A four fold increase in heart Gpx1 ...release of creatine kinase (a muscle enzyme) was significantly decreased." provenance.
- _5 wasQuotedFrom 11215509 provenance.